The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease – PubMed

https://pubmed.ncbi.nlm.nih.gov/25686106/

”Our findings suggest that the anti-inflammatory effects of caloric
restriction or ketogenic diets may be linked to BHB-mediated inhibition
of the NLRP3 inflammasome”

Youm YH, Nguyen KY, Grant RW, et al. The ketone metabolite
β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory
disease. Nat Med. 2015;21(3):263-269. doi:10.1038/nm.3804

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A drug that can stop tumors from growing — ScienceDaily

https://www.sciencedaily.com/releases/2021/04/210407174307.htm

 

Summary:
Scientists detail new work on NLRP3, an
intracellular complex that has been found to participate in
melanoma-mediated inflammation, leading to tumor growth and progression.
By inhibiting NLRP3, the researchers found, they can reduce
inflammation and the resultant tumor expansion.
 

 

 University of Colorado Anschutz Medical Campus. (2021, April 7). A drug that can stop tumors from growing. ScienceDaily. Retrieved May 16, 2021 from https://ift.tt/3huYIfI

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