Targeting insulin inhibition as a metabolic therapy in advanced cancer: A pilot safety and feasibility dietary trial in 10 patients – Nutrition

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Conclusion:

Preliminary data demonstrate that an insulin-inhibiting diet is safe and feasible in selected patients with advanced cancer. The extent of ketosis, but not calorie deficit or weight loss, correlated with stable disease or partial remission. Further study is needed to assess insulin inhibition as complementary to
standard cytotoxic and endocrine therapies.

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Almond consumption improved glycemic control and lipid profiles in patients with type 2 diabetes mellitus. – PubMed – NCBI

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Our results suggested that incorporation of almonds into a healthy diet has beneficial effects on adiposity, glycemic control, and the lipid profile, thereby potentially decreasing the risk for cardiovascular disease in patients with type 2 diabetes mellitus

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Novel treatment (new drug/intervention; established drug/procedure in new situation): Remission without insulin therapy on gluten-free diet in a 6-year old boy with type 1 diabetes mellitus

Novel treatment (new drug/intervention; established drug/procedure in new situation): Remission without insulin therapy on gluten-free diet in a 6-year old boy with type 1 diabetes mellitus (http://ift.tt/1CbqpNZ)

Abstract

A 5-year and 10-month old boy was diagnosed with classical type 1 diabetes mellitus (T1DM) without celiac disease. He started on a gluten-free diet after 2–3 week without need of insulin treatment. At the initiation of gluten-free diet, HbA1c was 7.8% and was stabilised at 5.8%–6.0% without insulin therapy. Fasting blood glucose was maintained at 4.0–5.0 mmol/l. At 16 months after diagnosis the fasting blood glucose was 4.1 mmol/l and after 20 months he is still without daily insulin therapy. There was no alteration in glutamic acid decarboxylase positivity. The gluten-free diet was safe and without side effects. The authors propose that the gluten-free diet has prolonged remission in this patient with T1DM and that further trials are indicated.

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